Skip to Main content Skip to Navigation
Master thesis

Intérêt du dosage du BNP et du NT-proBNP dans le diagnostic étiologique et l'orientation des patients admis dans un service d'urgence pour une dyspnée aigüe: étude prospective de 134 patients

Abstract : This prospective study done in the emergency department of the Nancy university hospital included 134 patients with a mean age of 76,8 years, presenting an acute dyspnea. They have been on advantage to a NT-proBNP dosage. The object was to determine the interest of those dosages in the etiologic diagnosis of a dyspnea, compared to the diagnosis of an mergency room doctor. BNP and NT-proBNP rates are used as references in the diagnosis of congestive heart failure. Their correlations are generally recognized in this pathology in the international literature. 48% of this sample presents a BNP higher than 100pg/mL 75 % of which is higher than 400pg/mL. For a treshold of 100pg/mL, which is a positive predictive value 82% and the negative predictive value 76%. NT-proBNP regains 72% of congestive heart failure, at a 1000 pg/mL treshold, with 85% sensitivity, 46% specificity, a positive predictive value of 67%, of and a negative one of 70%. BNP would have restored the diagnosis of congestive heart failure in 21,5% patients whose diagnosis of pulmonary disease has being hold. Their correlation betwwen BNP, NT-proBNP and creatinine has been confirmed. Therefore BNP seems to be a better reference in diagnosising congestive heart failure than the diagnosis of an emergency room doctor.
Document type :
Master thesis
Complete list of metadata

https://hal.univ-lorraine.fr/hal-01733464
Contributor : Colette Orange <>
Submitted on : Wednesday, March 14, 2018 - 3:53:21 PM
Last modification on : Friday, October 23, 2020 - 4:58:49 PM
Long-term archiving on: : Wednesday, September 5, 2018 - 7:29:51 AM

File

SCDMED_T_2005_BLANCHOT_SYLVAIN...
Files produced by the author(s)

Identifiers

  • HAL Id : hal-01733464, version 1

Citation

Sylvain Blanchot. Intérêt du dosage du BNP et du NT-proBNP dans le diagnostic étiologique et l'orientation des patients admis dans un service d'urgence pour une dyspnée aigüe: étude prospective de 134 patients. Sciences du Vivant [q-bio]. 2005. ⟨hal-01733464⟩

Share

Metrics

Record views

313

Files downloads

5146