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A novel device for measuring arterial stiffness using finger-toe pulse wave velocity: Validation study of the pOpmètre®

Abstract : BACKGROUND: The finger-toe pathway could be a good alternative for assessing arterial stiffness conveniently. AIM: To evaluate the accuracy of the pOpmètre®--a new device that measures finger-toe pulse wave velocity (ft-PWV). METHODS: The pOpmètre has two photodiode sensors, positioned on the finger and the toe. Pulse waves are recorded continuously for 20 seconds, and the difference in pulse wave transit time between toe and finger (ft-TT) is calculated. The travelled distance is estimated using subject height. Study 1 compared ft-PWV with carotid-femoral PWV (cf-PWV) obtained by the reference method (SphygmoCor®) in 86 subjects (mean age 53±20 years), including 69 patients with various pathologies and 17 healthy normotensives. Study 2 compared changes in ft-PWV and cf-PWV during a cold pressor test in 10 healthy subjects. Study 3 assessed repeatability in 45 patients. RESULTS: ft-PWV correlated significantly with cf-PWV (R2=0.43; P<0.0001). A better correlation was found in terms of transit time (R2=0.61; P<0.0001). The discrepancy between transit times was related to age. The cold pressor test induced parallel changes in cf-PWV and ft-PWV, with increased aortic stiffness that was reversible during recovery. Intra-session repeatability was very good, with a coefficient of variation of 4.52%. CONCLUSION: The pOpmètre® allows measurement of arterial stiffness in routine clinical practice. The greatest advantages of ft-PWV are simplicity, rapidity, feasibility, acceptability by patients and correct agreement with the reference technique. Further studies are needed to adjust for bias and to validate the pOpmètre in larger populations.
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Submitted on : Friday, March 23, 2018 - 10:18:43 AM
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Maureen Alivon, Thao Vo-Duc Phuong, Virginie Vignon, Erwan Bozec, Hakim Khettab, et al.. A novel device for measuring arterial stiffness using finger-toe pulse wave velocity: Validation study of the pOpmètre®. Archives of cardiovascular diseases, Elsevier/French Society of Cardiology, 2015, 108 (4), pp.227 - 234. ⟨10.1016/j.acvd.2014.12.003⟩. ⟨hal-01741443⟩



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