Propriétés bactériologiques de Parabacteroides distasonis

Abstract : The gut microbiota is a complex ecosystem whose homeostasis is essential to our health. Many factors impact its balance among whom the stress. Previous works have actually shown significant loss of Parabacteroides distasonis in different mice models of chronic stress. The exact role of this species that belong to the core microbiome of the gut is still unknown. The aim of this work was to identify P. distasonis bacterial characteristics such as growth kinetics, survival aptitude, surface properties as well as adhesion capacities to different kind of support. The results achieved allowed to show for the first time that P. distasonis is able to adhere on both inert support and intestinal cells Caco-2. Its ability to form biofilm on abiotic surface was also observed. The precise mechanisms of these phenomena remain to be explored in order to improve the knowledge on this species whose the stress-induced disappearance in the gut microbiota could be deleterious for the host.
Document type :
Master thesis
File URL :
http://docnum.univ-lorraine.fr/ulprive/BUS_M_2018_POTTIER_VANESSA.pdf
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https://hal.univ-lorraine.fr/hal-02010730
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Submitted on : Thursday, February 7, 2019 - 1:47:24 PM
Last modification on : Thursday, February 7, 2019 - 3:14:12 PM

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  • HAL Id : hal-02010730, version 1

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Vanessa Pottier. Propriétés bactériologiques de Parabacteroides distasonis. Biotechnologies. 2018. ⟨hal-02010730⟩

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