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RNA structure, maturation, interactions and functions

Abstract : RNAs play central roles in the fundamental processes of life and control of gene expression, and are also used as markers and therapeutic drugs in various pathologies, including cancer. The discovery of catalytic RNAs in the early 1980s entirely changed our view on the cellular functions of numerous cellular RNA molecules. This breakthrough led to a remarkable increase in knowledge on the folding of RNA molecules and their functional activities. Later on, the development of high-throughput sequencing techniques has allowed the identification of many new small and long non-coding RNAs (ncRNAs) in all life domains.
Keywords : RNA RNP
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Submitted on : Thursday, February 3, 2022 - 4:44:31 PM
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Yuri Motorin, Séverine Massenet. RNA structure, maturation, interactions and functions. Biochimie, Elsevier, 2019, 164, pp.1-2. ⟨10.1016/j.biochi.2019.07.013⟩. ⟨hal-02279819⟩



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