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Impact of the French Infectious Diseases Society's (SPILF) proposals for shorter antibiotic therapies

Abstract : OBJECTIVE: To compare the practices of French infection specialists related to antibiotic therapy duration between 2016 and 2018. METHODS: We conducted two identical surveys (in 2016 and 2018) targeting hospital-based infection specialists (medical physicians, pharmacists) who gave at least weekly advice on antibiotic prescriptions. The questionnaire included 15 clinical vignettes. Part A asked about the durations of antibiotic therapies they would usually advise to prescribers, and part B asked about the shortest duration they would be willing to advise for the same clinical situations. RESULTS: We included 325 specialists (165 in 2016 and 160 in 2018), mostly infectious disease specialists (82.4%, 268/325), members of antibiotic stewardship teams in 72% (234/325) of cases. Shorter antibiotic treatments (as compared with the literature) were advised to prescribers in more than half of the vignettes by 71% (105/147) of respondents in 2018, versus 46% (69/150) in 2016 (P<0.001). Guidelines used by participants displayed fixed durations for 77% (123/160) of cases in 2018 versus 21% (35/165) in 2016. Almost all respondents (89%, 131/160) declared they were aware of the 2017 SPILF's proposal. CONCLUSION: The release of guidelines promoting shorter durations of antibiotic therapy seems to have had a favourable impact on practices of specialists giving advice on antibiotic prescriptions.
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Submitted on : Wednesday, January 29, 2020 - 11:18:05 AM
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G. Macheda, A. Luc, G. Béraud, B. Castan, R. Gauzit, et al.. Impact of the French Infectious Diseases Society's (SPILF) proposals for shorter antibiotic therapies. Médecine et Maladies Infectieuses, Elsevier Masson, 2019, 49 (6), pp.456-462. ⟨10.1016/j.medmal.2019.07.005⟩. ⟨hal-02459159⟩



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