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Master thesis

Validation et optimisation d’une nouvelle méthode de détection des adénovirus humains

Abstract : Many epidemiological data indicate a significant involvement of viruses in the causes of waterborne illnesses (contact or consumption). Human adenoviruses, due to their persistence and prevalence in the environment make them a major public health concern and potential water quality indicators. Several viral detection methods exist to date, but their limitations are numerous. The recent advancements in the aptamer technology should make it possible to develop new techniques for virus detection. The objective of this study was to characterise a series of aptamers selected against human adenovirus serotype 2 for their binding capacities, affinities as well as specificities towards human adenoviruses. To do this, a technique similar to ELISA was used, but replacing antibodies with aptamers.
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Master thesis
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https://hal.univ-lorraine.fr/hal-02550745
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Submitted on : Wednesday, April 22, 2020 - 2:37:51 PM
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Brice Sanchez. Validation et optimisation d’une nouvelle méthode de détection des adénovirus humains. Microbiologie et Parasitologie. 2019. ⟨hal-02550745⟩

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