In its principle, Pulsed-Laser Ablation in Liquids (PLAL) appears as simple and versatile method to produce nanopar-ticles. However, due to its numerous processing parameters and their complex interdependence, this method has the main disadvantages of i) being hardly reproducible and ii) having a relatively weak productivity. The complexity of PLAL is well illustrated by the increase of the NPs concentration in the liquid as a function of irradiation time which may lead to an increasing absorption and/or scattering of the laser beam during the process. In a very recent paper, we showed that, even when using a laser wavelength which is far from the resonance band, the laser beam can be strongly attenuated due to the development and slow diffusion of a dense NPs layers in front of the target as the ablation proceeds. As a consequence, the ablation yield during the process can be considerably reduced. This raises the question of mass transport in PLAL that has been rarely considered in the literature up to now. In order to address this issue, we propose a novel design of PLAL setup, based on the irradiation of a high-speed rotating target. We show how the control of the nanoparticles mass transport allows us to considerably improve both repeatability and productivity of the process. Furthermore, the configuration of the proposed system enables the quantification and monitoring of both attenuation factor of the laser beam and ablation yield as a function of exposure time. Finally, the links between the laser energy attenuation, the ablation yield and repeatability of the colloids properties are revealed and discussed in terms of mass transport.