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Synthetic MRI is not yet ready for morphologic and functional assessment of patellar cartilage at 1.5 Tesla

Abstract : The purpose of this study was to compare morphologic assessment and relaxometry of patellar hyaline cartilage between conventional sequences (fast spin-echo [FSE] T2-weighted fat-saturated and T2-mapping) and synthetic T2 short-T1 inversion recovery (STIR) and T2 maps at 1.5 T magnetic resonance imaging (MRI). Method: The MRI examinations of the knee obtained at 1.5 T in 49 consecutive patients were retrospectively studied. There were 21 men and 28 women with a mean age of 45 ()+/-17.7 (SD) years (range: 18-88 years). Conventional and synthetic acquisitions were performed, including T2-weighted fat-saturated and T2-mapping sequences. Two radiologists independently compared patellar cartilage T2-relaxation time on conventional T2-mapping and synthetic T2-mapping images. A third radiologist evaluated the patellar cartilage morphology on conventional and synthetic T2-weighted images. The presence of artifacts was also assessed. Interobserver agreement for quantitative variables was assessed using intraclass correlation coefficient (ICC). Results: In vitro, conventional and synthetic T2 maps yielded similar mean T2 values 58.5 +/-2.3 (SD) ms and 58.8 +/-2.6 (SD) ms, respectively (P = 0.414) and 6% lower than the expected experimental values (P= 0.038). Synthetic images allowed for a 15% reduction in examination time compared to conventional images. On conventional sequences, patellar chondropathy was identified in 35 patients (35/49; 71%) with a mean chondropathy grade of 4.8 +/-4.8 (SD). On synthetic images, 28 patients (28/49; 57%) were diagnosed with patellar chondropathy, with a significant 14% difference (P = 0.009) and lower chondropathy scores (3.7 +/-4.9 [SD]) compared to conventional images. Motion artifacts were more frequently observed on synthetic images (18%) than on conventional ones (6%). The interobserver agreement was excellent for both conventional and synthetic T2 maps (ICC > 0.83). Mean
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Contributor : Jean-Sébastien Louis <>
Submitted on : Tuesday, May 11, 2021 - 3:28:25 PM
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C. Vogrig, J.-S. Louis, F. Avila, R. Gillet, G. Hossu, et al.. Synthetic MRI is not yet ready for morphologic and functional assessment of patellar cartilage at 1.5 Tesla. Diagnostic and Interventional Imaging, Elsevier, 2021, 102 (3), pp.181-187. ⟨10.1016/j.diii.2020.09.002⟩. ⟨hal-03224288⟩



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