Development and characterization of electrospun curcumin-loaded antimicrobial nanofibrous membranes - Université de Lorraine Access content directly
Journal Articles Textile Research Journal Year : 2021

Development and characterization of electrospun curcumin-loaded antimicrobial nanofibrous membranes

Javeed Awan
  • Function : Author
Saif Ur Rehman
  • Function : Author
Muhammad Kashif Bangash
  • Function : Author
Usman Ali
Muhammad Asad
  • Function : Author
Fiaz Hussain
  • Function : Author

Abstract

Curcumin is a naturally occurring hydrophobic polyphenol compound. It exhibits a wide range of biological activities such as antibacterial, anti-inflammatory, anti-carcinogenic, antifungal, anti-HIV, and antimicrobial activity. In this research work, antimicrobial curcumin nanofibrous membranes are produce by an electrospinning technique using the Eudragit RS 100 (C 19 H 34 ClNO 6 ) polymer solution enriched with curcumin. The morphology and chemistry of the membrane are analyzed using scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. Kirby Bauer disk diffusion tests are carried out to examine the antibacterial effectiveness of the membrane. Experimental results show that the nanofibers produced are of uniform thickness morphology and curcumin is successfully incorporated into the nanofibrous mat, while no chemical bonding was observed between curcumin and the polymer. The antimicrobial curcumin nanofibrous membranes can be effectively applied as antimicrobial barrier in a wide variety of medical applications such as wound healing, scaffolds, and tissue engineering.
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Dates and versions

hal-03324902 , version 1 (24-08-2021)

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Javeed Awan, Saif Ur Rehman, Muhammad Kashif Bangash, Usman Ali, Muhammad Asad, et al.. Development and characterization of electrospun curcumin-loaded antimicrobial nanofibrous membranes. Textile Research Journal, 2021, 91 (13-14), pp.1478-1485. ⟨10.1177/0040517520925514⟩. ⟨hal-03324902⟩
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