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Journal Articles Nature Communications Year : 2019

Limited antibody specificity compromises epitranscriptomic analyses

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Abstract

A controversial discussion on the occurrence of the RNA modification m1A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.

Dates and versions

hal-03480035 , version 1 (14-12-2021)

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Mark Helm, Frank Lyko, Yuri Motorin. Limited antibody specificity compromises epitranscriptomic analyses. Nature Communications, 2019, 10 (1), pp.5669. ⟨10.1038/s41467-019-13684-3⟩. ⟨hal-03480035⟩
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