The European Perspective and History on Biosimilars for the Treatment of Inflammatory Bowel Diseases - Université de Lorraine
Journal Articles Crohn's & Colitis 360 Year : 2021

The European Perspective and History on Biosimilars for the Treatment of Inflammatory Bowel Diseases

Abstract

Abstract With the expiration of biologics’ patents, biosimilars entered the market as a promising opportunity to reduce health-care costs in the field of inflammatory bowel diseases. Although biosimilars were initially poorly accepted, the growing evidence about their efficacy and safety has changed this situation, resulting in their widespread use. However, there is still an unmet need of improving patients’ education about biosimilars to minimize nocebo responses and to accept nonmedical switching. Looking to the future, the use of recently authorized adalimumab biosimilars and the first attempts of adopting different strategies of switching (eg, cross-, multiple-) will fill some residual knowledge gaps.

Dates and versions

hal-04214633 , version 1 (22-09-2023)

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Virginia Solitano, Ferdinando d'Amico, Leonardo da Rio, Laurent Peyrin-Biroulet, Silvio Danese. The European Perspective and History on Biosimilars for the Treatment of Inflammatory Bowel Diseases. Crohn's & Colitis 360, 2021, 3 (1), pp.otab012. ⟨10.1093/crocol/otab012⟩. ⟨hal-04214633⟩
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