Office- versus home-based evaluation of quality of life in heart failure with reduced ejection fraction: A randomized study - Université de Lorraine Accéder directement au contenu
Article Dans Une Revue International Journal of Cardiology Année : 2024

Office- versus home-based evaluation of quality of life in heart failure with reduced ejection fraction: A randomized study

Résumé


Background
Heart failure (HF) patients often experience poor health-related quality-of-life (HR-QoL). The Kansas City Cardiomyopathy Questionnaire (KCCQ) is frequently used for assessing HR-QoL in HF. Whether KCCQ scores vary in a clinical meaningful manner according to the setting (home vs office) where patients respond to the questionnaire is currently unknown.
Aims
Assess the differences in the responses to KCCQ-23 questionnaire when completed at home or office.
Methods
Randomized parallel-group study, including patients with HF with reduced ejection fraction (HFrEF). Primary outcome was home vs office comparison of overall summary score (KCCQ-OSS). Main secondary outcomes were clinical summary score (KCCQ-CSS) and total symptom score (KCCQ-TSS).
Results
A total of 100 patients were included in the study: 50 home vs 50 office. Mean age was 71 yrs. Most baseline characteristics were well balanced between groups, except male sex, MRA use, and prior HF hospitalizations which were more frequent in the home group. No statistically-significant between-group differences were found regarding KCCQ-OSS (median [percentile25–75]) scores: home 69.1 (42.0–86.5) vs office 63.1 (44.3–82.3) points, P-value = 0.59, or main secondary outcomes: KCCQ-CSS home 62.2 (46.5–79.9) vs office 68.1 (51.9–79.2) points, P-value = 0.69, and KCCQ-TSS home 84.7 (59.7–97.2) vs office 76.4 (66.7–94.4) points, P-value = 0.85. Results remained similar after adjustment for differences in baseline characteristics and using non-parametric regressions.
Conclusions
No major differences were found in KCCQ-23 scores regardless of whether the questionnaire was completed at home or office. These findings can be useful to make HR-QoL more accessible, allowing patients to respond at home using email or cell-phone applications.
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Dates et versions

hal-04651789 , version 1 (17-07-2024)

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Inês de Almeida Pinho, Maria João Pimentel, Cristina Oliveira, Maria Inês Matos, Catarina Vale, et al.. Office- versus home-based evaluation of quality of life in heart failure with reduced ejection fraction: A randomized study. International Journal of Cardiology, 2024, 413, pp.132341. ⟨10.1016/j.ijcard.2024.132341⟩. ⟨hal-04651789⟩
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