Skip to Main content Skip to Navigation
Theses

Nouvelles voies d'accès à des dérivés de l'acide L-iduronique

Abstract : This work deals with the development of new routes to L-iduronic acid derivatives from a cheap and abundant sugar, the methyl a-D-glucopyranoside. Many approaches were studied. First, the 1,6-anhydro-5-ulose compound preparation was achieved with the right configuration L-ido at C-5 and the adequat protection at C-4. Then, a large study of its deoxygenation was made by using different methods (radicals, ions...). The third part is focused on the septanoside chemistry (preparation and reactivity) as a new strategy to the L-ido compound derivatives. To finish, three auxiliary routes are tested from different molecules obtained previously in order to prepare L-idose derivatives
Document type :
Theses
Complete list of metadata

https://hal.univ-lorraine.fr/tel-01746310
Contributor : Thèses Ul Connect in order to contact the contributor
Submitted on : Thursday, March 29, 2018 - 10:30:42 AM
Last modification on : Wednesday, August 25, 2021 - 2:53:47 PM
Long-term archiving on: : Thursday, September 13, 2018 - 12:24:15 PM

File

SCD_T_2008_0011_JACKOWSKI.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : tel-01746310, version 1

Collections

Citation

Olivier Jackowski. Nouvelles voies d'accès à des dérivés de l'acide L-iduronique. Chimie. Université Henri Poincaré - Nancy 1, 2008. Français. ⟨NNT : 2008NAN10011⟩. ⟨tel-01746310⟩

Share

Metrics

Record views

56

Files downloads

195