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Spectroscopie d'impédance appliquée à la composition corporelle en néphrologie et en dialyse : caractérisation des facteurs d'influence

Abstract : The goal of this work is to study bioimpedance through different and particular people in nephrology (hemodialysis, renal disease or kidney graft), to assess this electrical engineering and the factors of onfluence that can change the measures or their meaning. We succeed to identify (through two bioimpedance instrument) several profiles of patients, according to their "response and behaviour" to this bioimpedance technique, depending on hemodialysis sessions, age, morbidity, presence of electrical device or after kidney transplantation. Through our population, we find a good validity of the electrical and physical measures. But when the values body composition are calculated from the electrical data, there is often aberrant values, concerning body composition, fluid compartment or the excess water. The main hypothesis is the existence of algorithms in the devices, compiled from statistics on healthy populations, with several corrective factors, but these algorithms probably don't fit with "particular" population. This work allows us to propose that what are the devices used, the patient might be his own measure witness. There is no study in the literature. Finally, an idea could be the existence of a specific tissue frequency, specific to each one, and different from the theoretical frequency of 50 kHz. This 50 kHz frequency corresponds to the highest cell membrane capacity and so characterizes the cell. Our study shows that the frequency corresponding to this highest reactance is precisely not 50 kHz. The hypothesis is the existence of a own characteristic frequency. Sudies remain to be done
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https://hal.univ-lorraine.fr/tel-01749571
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Joëlle Cridlig. Spectroscopie d'impédance appliquée à la composition corporelle en néphrologie et en dialyse : caractérisation des facteurs d'influence. Médecine humaine et pathologie. Université de Lorraine, 2013. Français. ⟨NNT : 2013LORR0040⟩. ⟨tel-01749571⟩

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