Skip to Main content Skip to Navigation
Theses

Corrélation entre la pression artérielle périphérique et la vitesse d'onde de pouls chez des sujets de plus de 80 ans institutionnalisés

Abstract : Background: Carotid-femoral pulse wave velocity (PWV) provides a comprehensive non-invasive assessment of arterial stiffness. PWV is now established as a strong marker of cardiovascular disease. The correlation between peripheral blood pressure and PWV and their respective influences on mortality have been poorly studied in the elderly. Our objective was to analyze this correlation in nursing home residents over 80 years of age. Results could ultimately be helpful in implementing strategies for diagnosis and long-term follow-up of the very elderly population. Methods: The PARTAGE (Predictive value of blood pressure and ARTerial stiffness in institutionalized very AGEd population) study is a 2-year cohort study of 1130 subjects living in 72 nursing homes in France and Italy. The correlation between baseline systolic and diastolic blood pressure (SBP and DBP) and baseline PWV (measured with a PulsePen® tonometer) was studied in 1071 subjects with available PWV measurements. Results: Correlations between peripheral blood pressure and PWV were significant but weak: r=0.24 for self-measured SBP, r=0.30 for casual SBP, r=0.11 for self measured DBP, r=0.14 for casual DBP and r=0.26 for casual pulse pressure (PP). A trend for a weaker correlation was observed in the higher age group for self measured SBP and in the lower ADL group for self measured SBP and DBP. The correlations were systematically higher in women compared to men (but did not reach statistical significance) and lower with advanced age group. The correlation was not impacted by antihypertensive. Conclusion: These findings suggest that SBP, DBP and PWV provide different information in the very elderly. The prospective, longitudinal, long term PARTAGE study results will allow further insight; provide additional in-depth information regarding the respective prognostic value of these two measurement methods. NCT00901355
Document type :
Theses
Complete list of metadatas

Cited literature [94 references]  Display  Hide  Download

https://hal.univ-lorraine.fr/tel-01750102
Contributor : Thèses Ul <>
Submitted on : Thursday, March 29, 2018 - 12:37:55 PM
Last modification on : Monday, December 21, 2020 - 5:09:57 PM

File

DDOC_T_2013_0113_MILJKOVIC.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : tel-01750102, version 1

Citation

Darko Miljkovic. Corrélation entre la pression artérielle périphérique et la vitesse d'onde de pouls chez des sujets de plus de 80 ans institutionnalisés. Médecine humaine et pathologie. Université de Lorraine, 2013. Français. ⟨NNT : 2013LORR0113⟩. ⟨tel-01750102⟩

Share

Metrics

Record views

84

Files downloads

2899