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Acquisition et traitement automatique de la pression buccale lors d'une interruption du débit respiratoire : eestimation de la pression alvéolaire pour la mesure de la résistance des voies aériennes

Abstract : Among others, investigation on hum an respiratory function involves the evaluation of its mechanical features. We built up a device for the measurement of the airway resistance and we integrated it ioto a device designed to investigate most mechanical parameters of the respiratory system. An evaluation of the alveolar pressure IS necessary to the determination of the aIrway resistance (Raw = (P Avl-P Mouth) / Airflow). Measurement of the airflow is rather easy but the evaluation of the alveolar pressure requires the use of an indirect method. One of these indirect methods consists in an sudden short airflow interruption. After the alveolar-mouth pressure equilibration, the alveolar pressure is evaluated from the mouth pressure. The present work deals, first, with the transitionnal perturbation accuracy after the airway occlusion. After words, we observed the alveolar-mouth pressure equilibration during interruptions on a lung simulator. The transitory perturbation was modelized by the thoery of the "coup de bélier". It recieved partial confirmation through altering the length of the alveolo-mouth connection, the elastance of trus walls and density of the gaz put into the simulator. Later on, we demonstrated that alveolo-mouth equilibration results from the transfer of a smalI amount of gaz (usually few milliliters which requires less th an 2 ms). It result from this work and its theoretical background (dynamic vs static analysis) that the alveoIar pressure can be measured whatever the physioIogical or pathologicaI onditions. The final exhibition of the measurements (mouth barograms) should allow easy access to pathoIogicaI resistance. This method is fillally iocluded into a precommercial device for the measurement of severaI other mechanical parameters of the respiratory system. We concluded about the possibilities on further research about the measurement of the alrway resistance through trus method and its use for clinical purposes
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Theses
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http://docnum.univ-lorraine.fr/prive/INPL_T_1991_HILT_B.pdf
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Submitted on : Thursday, March 29, 2018 - 1:32:59 PM
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  • HAL Id : tel-01752131, version 1

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Benoit Hilt. Acquisition et traitement automatique de la pression buccale lors d'une interruption du débit respiratoire : eestimation de la pression alvéolaire pour la mesure de la résistance des voies aériennes. Autre. Institut National Polytechnique de Lorraine, 1991. Français. ⟨NNT : 1991INPL054N⟩. ⟨tel-01752131⟩

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