Enquête ethnobotanique de six plantes médicinales maliennes : extraction, identification d?alcaloïdes - caractérisation, quantification de polyphénols : étude de leur activité antioxydante

Abstract : This work concerned the documentation of the traditional uses of six Malian medicinal plants, their phytochimic study and their antioxidant activity. Ethnobotanical survey was carried out using a semi-structured questionnairefor the determination of the various medicinal uses of these plants and showed that four of these plants would be used in the treatment of malaria and the two others, in the treatment of the painful and inflammatory affections; these last would be threatened of disappearance. The phytochimic study related to on the one hand the isolation of two alkaloids from V heterophylla their structures were elucidated using 1H- and 13C-NMR techniques and others spectral techniques as kokusaginine (a1) and montrifoline (a2) and on the one hand the determination of their contents total polyphenols through a spectrophotometric method as well as a polyphenol characterization using HPLC analysis. The results of this quantification and those of the antioxydant activity determined by ABTS and DPPH tests clearly showed the biological potential of these plants and could support their use in Malian traditional medicine
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Donatien Koné. Enquête ethnobotanique de six plantes médicinales maliennes : extraction, identification d?alcaloïdes - caractérisation, quantification de polyphénols : étude de leur activité antioxydante. Biologie végétale. Université Paul Verlaine - Metz, 2009. Français. ⟨NNT : 2009METZ014S⟩. ⟨tel-01752627⟩

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