Établissement et stabilisation d'une formulation lipidique équilibrée nutritionnellement : résolution des problèmes de texture et de flaveur, et validation nutritionnelle sur modèle animal

Abstract : Cardiovascular events are the major cause of death in France. Among the known risk factors, lipid intake is of growing interest, saturated fatty acids being too much consumed, and n-3 polyunsaturated fatty acids not enough. The aim of this PhD study is to design a spread with a lipid profile that can improve the whole lipid intake, and with cardiovascular events prevention as main goal.Four studies were conducted regarding this issue. Following the design of the optimal fatty acid profile for the product, it appeared necessary to study the solid phase recipe impact on the product texture, to achieve both nutritional and technological restrains.The design of the liquid phase recipe generated a study on the development of deleterious volatile compounds following the addition of a high proportion of fish oil in the formula. This work highlighted two phenomena linked to the emission of these molecules, one related to lipid oxidation, and the other to a contact with water.A technology of microencapsulation, which is original because of its production process and aim, was designed to ensure the protection of the active nutrients in the product matrix.Finally, a bioavailability study in rats showed that this food product is a powerful way of providing these nutrients. Incorporated in such a matrix, these molecules modified the lipid profile of the circulating and cerebral cells membrane, potentially improving the inflammatory and clotting status of the animals
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Submitted on : Friday, March 30, 2018 - 9:52:16 AM
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Virginie Dubois. Établissement et stabilisation d'une formulation lipidique équilibrée nutritionnellement : résolution des problèmes de texture et de flaveur, et validation nutritionnelle sur modèle animal. Alimentation et Nutrition. Institut National Polytechnique de Lorraine, 2007. Français. ⟨NNT : 2007INPL064N⟩. ⟨tel-01754532⟩

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