Dépistage du cancer de la prostate : perception et facteurs d'adhésion chez les hommes à risque familial

Abstract : The aim of this study was to assess the attitude, behavior and adherence factors to prostate cancer screening in men with a farnily history of prostate cancer. Two cohorts of men were studied. One from the University of California Los Angeles with flIst degree relatives of men with prostate cancer who have been identified in a previous study. Another cohort with flIst degree relatives of men with prostate cancer treated in three French university hospitals and they were offered a free PSA testing.Among men from the first cohort, 139 men participated (53 ±9), 92% were Caucasian, 29% had more than one affected relative with prostate cancer. Prostate cancer knowledge was good. Among men with good prostate cancer knowledge, only 62% thought that they were at higher risk than any American without a farnily history of prostate cancer. 62% of men had a PSA test and a digital rectal exarnination within two years. Men over 50, who had discussed with their farnily practitioner, who had a good knowledge about screening frequency, and men without comorbidity had undergone screening more often than others.Among men from the second cohort, 273 had undergone PSA test and 220 had normal PSA test completed questionnaires. 20% of men moderately deteriorated anxiety and 20% minirnally deteriorated quality of life during screening process. Factors associated with a deterioration of quality of life were having several affected relatives with prostate cancer, to be 50-60 years old, having an anxious personality, a high level of education and no children living at home. Talking about genetic problerns, 277 men filled out questionnaire and had undergone PSA test. 64% did not worry or a little about genetic predisposition while others worried a lot or extremely. Men who worried the most were ,those with a high level of chronic anxiety, who had undergone a previous screening.
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Luc Cormier. Dépistage du cancer de la prostate : perception et facteurs d'adhésion chez les hommes à risque familial. Médecine humaine et pathologie. Université Henri Poincaré - Nancy 1, 2002. Français. ⟨NNT : 2002NAN10293⟩. ⟨tel-01776041⟩

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