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Contribution to the study of mesenchymal stromal / stem cells heterogeneity, focus on surface markers and senescence

Abstract : Mesenchymal Stromal / Stem Cells (MSC) hold great potential and are currently the most used in clinical trials with cell-based treatments. MSC quality and therapeutic effectiveness are influenced by in vitro expansion but also by other factors such as donor parameters. To ameliorate the success rate of MSC therapies, this study focused on MSC heterogeneity. To put together cell characterization and ways to act when facing cell heterogeneity, this work was oriented toward the study of surface markers that can be monitored on living cells, and can serve to sort them.
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https://hal.univ-lorraine.fr/tel-03183242
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Submitted on : Friday, December 17, 2021 - 9:36:23 AM
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  • HAL Id : tel-03183242, version 1

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Laurie Targa. Contribution to the study of mesenchymal stromal / stem cells heterogeneity, focus on surface markers and senescence. Life Sciences [q-bio]. Université de Lorraine, 2019. English. ⟨NNT : 2019LORR0353⟩. ⟨tel-03183242⟩

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