Synthesis of Porphyrin, Chlorin and Phthalocyanine Derivatives by Azide-Alkyne Click Chemistry - Université de Lorraine Access content directly
Journal Articles Current Medicinal Chemistry Year : 2015

Synthesis of Porphyrin, Chlorin and Phthalocyanine Derivatives by Azide-Alkyne Click Chemistry

Abstract

The aim of this review is to provide a summary of the use of copper-catalyzed azide-alkyne cycloaddition (CuAAC) in the synthesis of porphyrin, chlorin and phthalocyanine derivatives for different types of therapeutic applications. The click reaction is a powerful and versatile tool for scientists working on the synthesis of various symmetrically and asymmetrically substituted tetrapyrrolic derivatives. For example, click chemistry is widely used for the elaboration of photosensitizer conjugates for photodynamic therapy applications. Other biological applications are also described.
No file

Dates and versions

hal-01270989 , version 1 (08-02-2016)

Identifiers

Cite

Samir Acherar, Ludovic Colombeau, Céline Frochot, Régis Vanderesse. Synthesis of Porphyrin, Chlorin and Phthalocyanine Derivatives by Azide-Alkyne Click Chemistry. Current Medicinal Chemistry, 2015, 22 (28), pp.3217-3254. ⟨10.2174/0929867322666150716115832⟩. ⟨hal-01270989⟩
137 View
0 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More