Skip to Main content Skip to Navigation
Journal articles

Synthesis and photophysical properties of the photoactivatable cationic porphyrin 5-(4-N-dodecylpyridyl)-10,15,20-tri(4-N-methylpyridyl)-21H,23H-porphyrin tetraiodide for anti-malaria PDT

Abstract : This article describes a new synthetic method for obtaining three water soluble porphyrins. The more sophisticated porphyrin [5-(4-N-dodecylpyridyl)-10,15,20-tri(4-N-methylpyridyl)-21H,23H-porphy rin tetraiodide], also named C12 porphyrin, was obtained through a three step methodology. The improvements, compared to syntheses described in the literature, mostly concern the purification procedures. The photophysical properties of the three porphyrins are described and the C12 porphyrin presents a very good O-1(2) yield compared to its chemical intermediates. This porphyrin seems to be a very promising candidate for PDT applications.
Document type :
Journal articles
Complete list of metadata

https://hal.univ-lorraine.fr/hal-01270996
Contributor : Lrgp Ul <>
Submitted on : Monday, February 8, 2016 - 4:46:29 PM
Last modification on : Tuesday, March 30, 2021 - 3:24:35 AM

Identifiers

Collections

Citation

Aurélie Stallivieri, Florent Le Guern, Régis Vanderesse, Esme Meledje, Giulio Jori, et al.. Synthesis and photophysical properties of the photoactivatable cationic porphyrin 5-(4-N-dodecylpyridyl)-10,15,20-tri(4-N-methylpyridyl)-21H,23H-porphyrin tetraiodide for anti-malaria PDT. Photochemical & Photobiological Sciences , Royal Society of Chemistry, 2015, 14 (7), pp.1290-1295. ⟨10.1039/c5pp00139k⟩. ⟨hal-01270996⟩

Share

Metrics

Record views

161