Lipophilic phthalocyanines for their potential interest in photodynamic therapy: synthesis and photo-physical properties

Abstract : Several phthalocyanines with different peripheral substituents were prepared and characterized by MALDI-TOF, H-1 NMR, UV-vis, fluorescence, and singlet oxygen quantum yields and retention time in HPLC normal phase. Zinc was used as a central metal ion to increase the photodynamic therapy efficiency. Phthalonitrile or 4-nitro phthalonitriles were used as starting materials. The influence of lipophilicity on the photophysical and photochemical properties was evaluated.
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Article dans une revue
Tetrahedron, Elsevier, 2013, 69 (47), pp.10116-10122. 〈10.1016/j.tet.2013.09.035〉
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https://hal.univ-lorraine.fr/hal-01278786
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Soumis le : mercredi 24 février 2016 - 18:10:42
Dernière modification le : mardi 24 juillet 2018 - 16:43:08

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Albert Moussaron, Philippe Arnoux, Régis Vanderesse, Estelle Sibille, Patrick Chaimbault, et al.. Lipophilic phthalocyanines for their potential interest in photodynamic therapy: synthesis and photo-physical properties. Tetrahedron, Elsevier, 2013, 69 (47), pp.10116-10122. 〈10.1016/j.tet.2013.09.035〉. 〈hal-01278786〉

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