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Solvent extraction and purification of rosmarinic acid from supercritical fluid extraction fractionation waste: Economic evaluation and scale-up

Abstract : Industry is increasingly interested in natural food preservatives, antimicrobial, and antioxidants due to their beneficial effects. The use of plant waste also presented itself to be a great opportunity in recovered bioactive compounds remaining in the residue. In this work, bioactive compounds were obtained from Rosmarinus officinalis in two different ways: firstly the supercritical fractionated rosemary extract with different composition was obtained from the plant material, and secondly a potent antioxidant-rosmarinic acid (RA) was successfully extracted from the plant waste. A purification process scale-up of RA was proposed using GRAS solvent, and an economic evaluation was made for the overall process. A complete process to obtain bioactive compounds, antimicrobial (supercritical fluid extraction and fractionation extraction) and antioxidant (solvent extraction) was developed.
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https://hal.univ-lorraine.fr/hal-01281227
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Submitted on : Tuesday, March 1, 2016 - 6:20:41 PM
Last modification on : Monday, May 4, 2020 - 5:00:04 PM

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Andre Wust Zibetti, Abdelkarim Aydi, Mayra Arauco Livia, Ariovaldo Bolzan, Danielle Barth. Solvent extraction and purification of rosmarinic acid from supercritical fluid extraction fractionation waste: Economic evaluation and scale-up. Journal of Supercritical Fluids, Elsevier, 2013, 83, pp.133-145. ⟨10.1016/j.supflu.2013.09.005⟩. ⟨hal-01281227⟩

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