This article presents the specific classes of reactions considered for modeling the oxidation of the two types of oxygenated molecules which are the most usually considered in biofuels: alcohols and esters. Using models for hydrocarbon oxidation as a reference, this paper also reports the major changes to be considered for the kinetic data of the main reaction classes which are the same as those taken into account for non-oxygenated reactants. Details are given in the case of hydrogen atom abstractions, radical decompositions by beta-scission, RO2 . radical chemistry, with especially intramolecular isomerizations, and reactions leading to unsaturated products and HO2 radicals.