Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus

Abstract : Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.
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Bioorganic and Medicinal Chemistry Letters, Elsevier, 2013, 23 (5), pp.1274-1278. 〈10.1016/j.bmcl.2013.01.004〉
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https://hal.univ-lorraine.fr/hal-01494086
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Soumis le : mercredi 22 mars 2017 - 16:40:23
Dernière modification le : lundi 25 juin 2018 - 15:36:03

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Mebarek Bahnous, Abdelmalek Bouraiou, Meryem Chelghoum, Sofiane Bouacida, Thierry Roisnel, et al.. Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2013, 23 (5), pp.1274-1278. 〈10.1016/j.bmcl.2013.01.004〉. 〈hal-01494086〉

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