Journal Articles Bioorganic and Medicinal Chemistry Letters Year : 2013

Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus

Abstract

Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.

Dates and versions

hal-01494086 , version 1 (22-03-2017)

Identifiers

Cite

Mebarek Bahnous, Abdelmalek Bouraiou, Meryem Chelghoum, Sofiane Bouacida, Thierry Roisnel, et al.. Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus. Bioorganic and Medicinal Chemistry Letters, 2013, 23 (5), pp.1274-1278. ⟨10.1016/j.bmcl.2013.01.004⟩. ⟨hal-01494086⟩
118 View
0 Download

Altmetric

Share

More