Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes - Université de Lorraine
Journal Articles MedChemComm Year : 2014

Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes

Abstract

Several amphiphilic, chalcogen-based redox modulators have been synthesized which exhibit a widespread, yet in some instances also selective, biological activity which is most likely based on their ability to modulate the intracellular redox balance and to interact with cellular membranes and specific proteins.

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Chemical Sciences

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https://hal.univ-lorraine.fr/hal-01494556

Submitted on : Thursday, March 23, 2017-4:19:47 PM

Last modification on : Thursday, April 11, 2024-1:08:14 PM

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hal-01494556 , version 1 (23-03-2017)

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Peng Du, Uma M. Viswanathan, Khairan Khairan, Tomislav Buric, Nathaniel E. B. Saidu, et al.. Synthesis of amphiphilic, chalcogen-based redox modulators with in vitro cytotoxic activity against cancer cells, macrophages and microbes. MedChemComm, 2014, 5 (1), pp.25-31. ⟨10.1039/c3md00204g⟩. ⟨hal-01494556⟩

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