Poly-guanidinoethylphenylethers organised around a benzene ring: Synthesis and evaluation of their antibacterial and cytotoxic properties

Abstract : A new family of poly-guanidinium species with a benzene core as the organising agent has been developed. Their antibacterial properties have been evaluated against reference Gram positive and Gram negative bacteria, and their cytotoxicity against eukaryotic cells. Most of these compounds exhibited Minimum Inhibitory Concentrations in the micromolar range.
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Bioorganic and Medicinal Chemistry Letters, Elsevier, 2014, 24 (20), pp.4791-4793. 〈10.1016/j.bmcl.2014.09.013〉
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https://hal.univ-lorraine.fr/hal-01494563
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Soumis le : jeudi 23 mars 2017 - 16:20:01
Dernière modification le : mardi 16 janvier 2018 - 10:24:44

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Hugues Massimba Dibama, Maxime Mourer, Raphaël E. Duval, Jean-Bernard Regnouf-De-Vains. Poly-guanidinoethylphenylethers organised around a benzene ring: Synthesis and evaluation of their antibacterial and cytotoxic properties. Bioorganic and Medicinal Chemistry Letters, Elsevier, 2014, 24 (20), pp.4791-4793. 〈10.1016/j.bmcl.2014.09.013〉. 〈hal-01494563〉

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