Skip to Main content Skip to Navigation
Journal articles

Kinetic study of chlordecone orally given to laying hens (Gallus domesticus)

Abstract : The former use of chlordecone (CLD) in the French West Indies has resulted in long-term pollution of soils. In this area, CLD may be transferred into eggs of hens reared outdoors, through soil ingestion. In order to assess this risk, a kinetic study involving the contamination of laying hens (22 weeks of age) with a diet containing 500 mu g CLD kg(-1) during 42 d, followed by a depuration period of 35 d was carried out. Forty-four hens were sequentially slaughtered all over the experimental period and their liver, egg, abdominal fat and serum were collected. Two additional edible tissues, pectoral and leg muscles, were collected in hens slaughtered at the end of the contamination period. The depuration half-life of CLD in liver, egg, abdominal fat and serum was estimated at 5.0 +/- 0.38 (mean +/- SE), 5.5 +/- 0.29, 5.3 +/- 0.37 and 5.1 +/- 0.66 d, respectively. CLD concentration at the end of the contamination period reached 1640 +/- 274,460 +/- 41,331 +/- 23, and 213 +/- 8.5 mu g kg(-1) fresh matter (FM), respectively. The corresponding concentrations in pectoral and leg muscles were 119 +/- 8.4, 127 +/- 11 mu g kg(-1) FM, respectively. The steady state carry over rate of CLD in eggs reached 43 +/- 7.6%. This experiment demonstrates the preferential accumulation of CLD in liver, its significant transfer to eggs and its quite short half-life. It is concluded that raising hens on even mildly contaminated areas would lead to products exceeding the regulatory maximum residue limit of 20 mu g CLD kg(-1).
Document type :
Journal articles
Complete list of metadata

https://hal.univ-lorraine.fr/hal-01562172
Contributor : Urafpa Ul <>
Submitted on : Thursday, July 13, 2017 - 4:35:49 PM
Last modification on : Saturday, July 31, 2021 - 3:56:35 AM

Identifiers

Citation

Catherine Jondreville, Agnès Fournier, Maurice Mahieu, Cyril Feidt, Harry Archimède, et al.. Kinetic study of chlordecone orally given to laying hens (Gallus domesticus). Chemosphere, Elsevier, 2014, 114, pp.275-281. ⟨10.1016/j.chemosphere.2014.05.008⟩. ⟨hal-01562172⟩

Share

Metrics

Record views

191