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Journal Articles Sensors and Actuators B: Chemical Year : 2017

Biochip based on arrays of switchable magnetic nano-traps


Magnetic biochips based on switchable magnetic nano-traps were developed and optimized so as to enable faster bio-assays via a reduction of steps and the efficient capture of analytes in a sample test solution. Nano-traps are based on snake shaped magnetic nanowires made by microelectronic technics from a thin magnetic layer. This optimized design ensures high local fields when the trap is activated and reduced stray fields when deactivated with respect to previous designs. Our proof-of-concept model consists to determine the anchorage of synthetic peptides in a bilayer enveloping magnetic beads by revealing their presence via fluorescently labeled immunoglobulins elicited against the native proteins of the said exposed peptides.
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hal-01686947 , version 1 (23-01-2018)



Christopher Vautrin, Maria Vyazmensky, Stanislav Engel, Stephan Mc. Murtry, Michel Hehn, et al.. Biochip based on arrays of switchable magnetic nano-traps. Sensors and Actuators B: Chemical, 2017, 251, pp.699-705. ⟨10.1016/j.snb.2017.05.084⟩. ⟨hal-01686947⟩
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