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Impact of Neonatal Factors and Nutrition on Kidney Size in 5-Year-Old Preterm-Born Children

Abstract : OBJECTIVE: The aim of this article is to evaluate the influence of neonatal factors on kidney size in 5-year-old preterm-born children. STUDY DESIGN: Preterm-born children were examined at 5 years with kidney ultrasound. RESULT: A total of 20 children were evaluated. Their gestational age (GA) was 29.3 ± 1.5 weeks, birth weight 1,321 ± 323 g. On Day 28, protein intake was (median, range) 2.8 (1.7-3.6 g/kg) g/kg, protein/total calories ratio 2.8 (range, 1.7-3.3 g/100 kcal) g/100 kcal. At 5 years, their systolic blood pressure was 97 mm Hg (range, 84-115 mm Hg). All had normal estimated glomerular filtration rate. Protein intake on Day 28 and protein/calories ratio on Day 28 were associated with a low total relative renal volume, respectively, β =  - 37 ± 15, p = 0.03; β =  - 50 ± 19, p = 0.03, after adjustment on GA, neonatal morbidities, and body mass index (multivariate linear regression). Kidney size was not associated with protein intake at 5 years. CONCLUSION: Improving protein prescription in the neonatal period could have an impact on kidney size in childhood in preterm-born children.
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https://hal.univ-lorraine.fr/hal-01713061
Contributor : Devah Ul <>
Submitted on : Tuesday, February 20, 2018 - 10:33:57 AM
Last modification on : Tuesday, October 13, 2020 - 10:47:39 AM

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Sorana Galu, Jean-Michel Hascoët, Rachel Vieux. Impact of Neonatal Factors and Nutrition on Kidney Size in 5-Year-Old Preterm-Born Children. American Journal of Perinatology, Thieme Publishing, 2015, 32 (03), pp.219 - 224. ⟨10.1055/s-0034-1374816⟩. ⟨hal-01713061⟩

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