A collaborative sequential meta-analysis of individual patient data from randomized trials of endovascular therapy and tPA vs. tPA alone for acute ischemic stroke: T h R omb E ctomy A nd t PA (TREAT) analysis: statistical analysis plan for a sequential meta-analysis performed within the VISTA-Endovascular collaboration
Rachael Macisaac
(1)
,
Pooja Khatri
(2)
,
Martin Bendszus
(3)
,
Serge Bracard
(4, 5)
,
Joseph Broderick
(2)
,
Bruce Campbell
(6)
,
Alfonso Ciccone
(7)
,
Antoni Dávalos
(8)
,
Stephen Davis
(6)
,
Andrew Demchuk
(9)
,
Hans-Christoph Diener
(10)
,
Diederik Dippel
(11)
,
Geoffrey Donnan
(12)
,
Jens Fiehler
(13)
,
David Fiorella
(14)
,
Mayank Goyal
(15)
,
Werner Hacke
(16)
,
Michael Hill
(9)
,
Reza Jahan
(17)
,
E Jauch
(18)
,
Tudor Jovin
(19)
,
Chelsea Kidwell
(20)
,
David Liebeskind
(17)
,
Charles Majoie
(21)
,
Sheila Cristina Ouriques Martins
(22)
,
Peter Mitchell
(12)
,
J. Mocco
(23)
,
Keith Muir
(24, 25)
,
Raul Nogueira
(26)
,
Jeffrey Saver
(17)
,
Wouter Schonewille
(27)
,
Adnan Siddiqui
(28)
,
Götz Thomalla
(13)
,
Thomas Tomsick
(2)
,
Aquilla Turk
(18)
,
Philip White
(29)
,
Osama Zaidat
(30)
,
Kennedy Lees
(1)
1
Institute of Cardiovascular and Medical Sciences [Glasgow]
2 UC - University of Cincinnati
3 Heidelberg University Hospital [Heidelberg]
4 Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy]
5 IADI - Imagerie Adaptative Diagnostique et Interventionnelle
6 The Royal Melbourne Hospital
7 ASST - Azienda Socio Sanitaria Territoriale di Mantova [Mantova, Italy]
8 Hospital Universitario Germans Trias I Pujol
9 University of Calgary
10 Uniklinik Essen - Universitätsklinikum Essen [Universität Duisburg-Essen]
11 Erasmus MC - Erasmus University Medical Center [Rotterdam]
12 University of Melbourne
13 UKE - Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg]
14 SBU - Stony Brook University [SUNY]
15 Hotchkiss Brain Institute
16 Universität Heidelberg [Heidelberg] = Heidelberg University
17 UCLA - University of California [Los Angeles]
18 MUSC - Medical University of South Carolina [Charleston]
19 PITT - University of Pittsburgh
20 University of Arizona
21 AMC - Academic Medical Center - Academisch Medisch Centrum [Amsterdam]
22 HCPA - Hospital de Clínicas de Porto Alegre
23 MSSM - Icahn School of Medicine at Mount Sinai [New York]
24 Institute of Neurosciences and Psychology [Glasgow]
25 Southern General Hospital, Glasgow
26 Massachusetts General Hospital [Boston]
27 St. Antonius Hospital [Nieuwegein]
28 SUNY Buffalo - University at Buffalo [SUNY]
29 Newcastle University [Newcastle]
30 Medical College of Wisconsin
2 UC - University of Cincinnati
3 Heidelberg University Hospital [Heidelberg]
4 Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy]
5 IADI - Imagerie Adaptative Diagnostique et Interventionnelle
6 The Royal Melbourne Hospital
7 ASST - Azienda Socio Sanitaria Territoriale di Mantova [Mantova, Italy]
8 Hospital Universitario Germans Trias I Pujol
9 University of Calgary
10 Uniklinik Essen - Universitätsklinikum Essen [Universität Duisburg-Essen]
11 Erasmus MC - Erasmus University Medical Center [Rotterdam]
12 University of Melbourne
13 UKE - Universitaetsklinikum Hamburg-Eppendorf = University Medical Center Hamburg-Eppendorf [Hamburg]
14 SBU - Stony Brook University [SUNY]
15 Hotchkiss Brain Institute
16 Universität Heidelberg [Heidelberg] = Heidelberg University
17 UCLA - University of California [Los Angeles]
18 MUSC - Medical University of South Carolina [Charleston]
19 PITT - University of Pittsburgh
20 University of Arizona
21 AMC - Academic Medical Center - Academisch Medisch Centrum [Amsterdam]
22 HCPA - Hospital de Clínicas de Porto Alegre
23 MSSM - Icahn School of Medicine at Mount Sinai [New York]
24 Institute of Neurosciences and Psychology [Glasgow]
25 Southern General Hospital, Glasgow
26 Massachusetts General Hospital [Boston]
27 St. Antonius Hospital [Nieuwegein]
28 SUNY Buffalo - University at Buffalo [SUNY]
29 Newcastle University [Newcastle]
30 Medical College of Wisconsin
Pooja Khatri
- Fonction : Auteur
- PersonId : 786399
- ORCID : 0000-0002-7344-8266
Hans-Christoph Diener
- Fonction : Auteur
- PersonId : 891161
Jens Fiehler
- Fonction : Auteur
- PersonId : 762066
- ORCID : 0000-0001-8533-7478
David Liebeskind
- Fonction : Auteur
- PersonId : 786400
- ORCID : 0000-0002-5109-8736
Jeffrey Saver
- Fonction : Auteur
- PersonId : 786401
- ORCID : 0000-0001-9141-2251
Philip White
- Fonction : Auteur
- PersonId : 786402
- ORCID : 0000-0001-6007-6013
Osama Zaidat
- Fonction : Auteur
- PersonId : 786403
- ORCID : 0000-0003-4881-4698
Résumé
Endovascular treatment has been shown to restore blood flow effectively. Second-generation medical devices such as stent retrievers are now showing overwhelming efficacy in clinical trials, particularly in conjunction with intravenous recombinant tissue plasminogen activator.