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Master thesis

Développement et validité de l'auto-questionnaire DyNaChron : évaluation de la gêne liée au dysfonctionnement naso-sinusien chronique

Abstract : Statement of problem : Nasal ans sinus diseases generate six main symptoms, with important physical and psychosocial repercussions that we propose to measure with a self-report questionnaire exploring the chronic nasal dysfunction (CND) independantly of itsetiologies. Methods of study: The study was conducted in two palis : 1) development of a questionnaire in French using several expelis and testing face validity, 2) validity testing,including construct validity by factor analysis, reproducibility by intraclass correlation coefficient and Sland and Altman plots, and sensitivity to change by standardized response means, on a large sample of patients in a prospective multicenter study. Results : DyNaChron, a seventy-eight items questionnaire, divided in six dimensions and exploring both physical and psychosocial repercussions of CND was created. Seven hundred and thirty one patients fulfilled the questionnaire at first and fifty hundred and two again twenty days later. The questionnaire structure was confirmed to be multidimensional, composed of six domains (six factors explaining 68.7% of the variance) with two dimensions in each domain. Convergent validity analysis was confirmed. Cronbach's alpha coefficient was high (0.93 to 0.96). Intra-class coefficient correlationranged from 0.8 to 0.91. Sensitivity to change was higher in patients improved than in those deteriorated. Conclusions : DyNaChron questionnaire was created and validated to be used in research. Further consideration will be taken for shortening in order to use this instrument in clinical practice.
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Master thesis
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https://hal.univ-lorraine.fr/hal-01733196
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Submitted on : Wednesday, March 14, 2018 - 3:39:56 PM
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  • HAL Id : hal-01733196, version 1

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Sophie Kacha. Développement et validité de l'auto-questionnaire DyNaChron : évaluation de la gêne liée au dysfonctionnement naso-sinusien chronique. Sciences du Vivant [q-bio]. 2009. ⟨hal-01733196⟩

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