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Master thesis

Apport du Morpho-TEP au 18F-fluorodéoxyglucose dans la recherche de primitif inconnu

Abstract : Target and method : This retrospective study, performed on 37 patients, gave us the opportunity to evaluate the impact of [exponent 18]F-FDG PET/CT for cancer of unknown primary. The first aim of our study was to study the sensitivity of the exam to detect the primary, after a negative work-up. We also evaluated the ability of the procedure to assess for the staging ofthe disease, and we judged the impact of the results on management and survival of those patients. Result : The FDG PET/CT led to the detection of the primary in 14 patients out of 37, after a negative work-up including on average 5 examinations. For 10 patients, the FDG PET/CT allowed the detection of additional metastases. The patient's management wasaltered in more than one third of the patients, however without obvious impact on the overall survival of these patients, the prognostic of which is usually badConclusion : The [exponent 18]F-FDG PET/CT appears to be a valuable tool for detection of unknown primary, with frequent impact on the patient's management. These results should be confirmed in a prospective way, in particular for judging the impact of the reshts of the exam on the survival.
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Master thesis
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Submitted on : Wednesday, March 14, 2018 - 4:32:45 PM
Last modification on : Friday, October 23, 2020 - 4:58:43 PM
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  • HAL Id : hal-01734298, version 1


Claire Bruna. Apport du Morpho-TEP au 18F-fluorodéoxyglucose dans la recherche de primitif inconnu. Sciences du Vivant [q-bio]. 2006. ⟨hal-01734298⟩



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