Récurrence de l'infection par le virus de l'hépatite C (VHC) après transplantation du foie pour hépatopathie due au VHC : facteurs liés à l'hôte et facteurs viraux impliqués dans la survenue et la gravité de la récurrence de l'hépatite virale C

Abstract : Cirrhosis due to chronic infection by hepatitis C virus (HCV), associated or not to a primary hepatocarcinoma, has become the first indication of liver transplantation. Graft reinfection by HCV is considered to be systematic while its prognosis is variable from one patient to another. A better knowledge of factors implicated in the occurrence and severity of hepatitis C recurrence is crucial in order to make optimal patients' monitoring. This article aims to present available data in this field, clarifying the role of viral factors (viral load, genotype, evolution of viral quasispecies) and host-related factors (immune response) which could take part in the development of hepatitis C recurrence.
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https://hal.univ-lorraine.fr/hal-02014523
Contributor : Evelyne Schvoerer <>
Submitted on : Monday, February 11, 2019 - 4:09:44 PM
Last modification on : Friday, March 8, 2019 - 2:36:03 PM

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Evelyne Schvoerer, C. Thumann, E. Soulier, C. Royer, S. Fafi-Kremer, et al.. Récurrence de l'infection par le virus de l'hépatite C (VHC) après transplantation du foie pour hépatopathie due au VHC : facteurs liés à l'hôte et facteurs viraux impliqués dans la survenue et la gravité de la récurrence de l'hépatite virale C. Pathologie Biologie, Elsevier Masson, 2006, 54 (10), pp.556-560. ⟨10.1016/j.patbio.2006.07.027⟩. ⟨hal-02014523⟩

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