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Chemoenzymatic preparation of germacrene analogues

Abstract : A small library of novel germacrenes was generated using a combination of two plant enzymes, germacrene A synthase, and D synthase and modified farnesyl diphosphate (FDP) analogues. This chemoenzymatic approach allows the preparation of potentially valuable volatiles for biological studies.
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Submitted on : Friday, February 15, 2019 - 6:09:25 PM
Last modification on : Tuesday, May 10, 2022 - 3:38:03 PM

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Oscar Cascón, Sabrina Touchet, David Miller, Verónica González, Juan Faraldos, et al.. Chemoenzymatic preparation of germacrene analogues. Chemical Communications, 2012, 48 (78), pp.9702-9704. ⟨10.1039/c2cc35542f⟩. ⟨hal-02021355⟩



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