The conservation of built heritage requires a good knowledge of the materials and the history of the monument in question. One objective of the SACRE 1 project is to establish the health record of a monument. Chambord castle was built out of tuffeau limestone in 1519. This limestone, which comes from the Loire Valley, is extremely fragile, causing spalling and exfoliation to occur on the surface of the stone. Two parts of the castle are studied in this paper: the south façade, entrance to the castle, and the east tower. The mapping of the different origins and dates of the stones forms the basis of the health record of the castle. The comparison between this mapping and the location of damages on the façades shows different type and degree of degradation concerning tuffeau. The topography and the orientation of the building are also significant parameters that contribute to the development of specific types of degradation.