Skip to Main content Skip to Navigation
Journal articles

Chest X-ray quantification of admission lung congestion as a prognostic factor in patients admitted for worsening heart failure from the ICALOR cohort study

Abstract : Introduction: Chest X-ray (CXR) widely used, but the prognostic value of congestion quantification using CXR remains uncertain. The main objective of the present study was to assess whether initial quantification of lung congestion evaluated by CXR [and its interplay with estimated plasma volume status (ePVS)] in patients with worsening heart failure (WHF) is associated with in-hospital and short-term clinical outcome. Methods: We studied 117 patients hospitalized for WHF in the ICALOR HF disease management program. Pulmonary congestion was estimated using congestion score index (CSI, range 0 to 3) evaluated from 6 lung areas on CXR. Systemic congestion was assessed by ePVS. Logistic regression analysis was used to assess length of stay and the composite of all-cause death or HF re-hospitalization at 90 days. Results: Patients were divided according to the median of admission CSI (median=2.20) and ePVS (median=5.38). Higher CSI was significantly associated with higher pulmonary arterial systolic pressure in multivariable models. Multivariable models showed patients with high CSI/high ePVS had a 6-day longer length of stay [OR (95%CI)=6.78 (1.82-29.79), p<0.01] and 5-fold higher risk of 90-day composite outcome [OR (95%CI)=5.13 (1.26-25.11) p=0.03] compared to patients with low CSI/low ePVS, while other configurations (either isolated high CSI or high ePVS) yielded neutral associations. Furthermore, CSI and ePVS significantly improved reclassification on top of clinical covariates for the composite outcome [Net reclassification index=37.3% (0.52-87.0), p=0.046]. Conclusion: An admission assessment of pulmonary and systemic congestion in WHF patients using CSI and ePVS can identify a cluster of high-risk patients at short-term outcomes.
Complete list of metadata

Cited literature [57 references]  Display  Hide  Download

https://hal.univ-lorraine.fr/hal-02557291
Contributor : Erwan Bozec <>
Submitted on : Tuesday, April 28, 2020 - 4:23:26 PM
Last modification on : Thursday, January 21, 2021 - 1:48:04 PM

Files

CSI_PVS_ICALOR_IJC2020.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Masatake Kobayashi, Matthieu Bercker, Olivier Huttin, Sarah Pierre, Nicolas Sadoul, et al.. Chest X-ray quantification of admission lung congestion as a prognostic factor in patients admitted for worsening heart failure from the ICALOR cohort study. International Journal of Cardiology, Elsevier, 2020, 299, pp.192-198. ⟨10.1016/j.ijcard.2019.06.062⟩. ⟨hal-02557291⟩

Share

Metrics

Record views

124

Files downloads

111