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Comparative study of the production of coumarins and furanocoumarins in three Ruteae species

Abstract : Within specialized metabolites, coumarins and furanocoumarins represent a wide group of structurally diverse compounds and are specially produced in plants belonging to the Rutaceae family. Here we performed the furanocoumarin and coumarin-targeted chemical characterization of three Ruteae species collected from Algeria. Detection and quantification of 27 coumarins and furanocoumarins extracted from stems and leaves was carried out by UHPLC-MS. We highlighted significant chemical differences between these plants. Ruta chalepensis L. is the highest producer with 24.83 mmol/g dry material in stems and 15.70 mmol/g dry materials in leaves while Haplophyllum tuberculatum (Forsk.) is the lowest producer. We also showed a surprising chemical diversity between R. chalepensis L and R. angustifolia Pers. This chemical diversity might, therefore, be a helpful tool for phylogenetic identification of plants.
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Saida Bergheul, Mariana Limones-Mendez, Jeremy Grosjean, Alain Hehn, Alexandre Olry, et al.. Comparative study of the production of coumarins and furanocoumarins in three Ruteae species. Indian Journal of Natural Products and Resources, New Delhi National Institute of Science Communication and Information Resources, 2019, 10 (2), pp.137 - 142. ⟨hal-02917590⟩

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