The objective of the present article is to review the literature on strengths use and development in the workplace. This review (1) presents a summary of the outcomes of strengths use in organizations, and (2) proposes a general intervention model facilitating strengths development in the workplace. A systematic review was used to summarize the outcomes of studies on strengths use at work, whereas a narrative review was employed to examine the main strengths development interventions available, and to propose an integrative model. Results indicate that strengths use is associated with job satisfaction, work engagement, well-being, and work performance. Furthermore, scholars and professionals use similar intervention strategies that can be summarized in a five-step integrative model to promote strengths development in organizations. We discuss the theoretical and practical implications, as well as avenues for future research.