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Estimated plasma volume status in heart failure: clinical implications and future directions

Abstract : Congestion is one of the main predictors of poor outcome in patients with heart failure (HF). Assessing and monitoring congestion is essential for optimizing HF therapy. Among the various available methods, serial measurements of estimated plasma volume (ePVS) using routine blood count and/or body weight (e.g., the Strauss, Duarte, Hakim formulas) may be useful in HF management. Further prospective study is warranted to determine whether ePVS can help optimize decongestion therapy (loop diuretics, mineralocorticoid receptor antagonists, SGLT2i) in various HF settings. This narrative review summarizes the recent evidence supporting the association of ePVS with clinical congestion and outcome(s) and discusses future directions for monitoring ePVS in HF.
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https://hal.univ-lorraine.fr/hal-03109061
Contributor : Erwan Bozec <>
Submitted on : Wednesday, January 13, 2021 - 3:52:36 PM
Last modification on : Sunday, January 17, 2021 - 6:42:53 PM

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Masatake Kobayashi, Nicolas Girerd, Kevin Duarte, Tahar Chouihed, Taishiro Chikamori, et al.. Estimated plasma volume status in heart failure: clinical implications and future directions. Clinical Research in Cardiology, Springer Verlag, 2021, ⟨10.1007/s00392-020-01794-8⟩. ⟨hal-03109061⟩

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