Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF) - Université de Lorraine Access content directly
Journal Articles PLoS ONE Year : 2021

Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF)

Leila Abid (1) , Salma Charfeddine (2) , Ikram Kammoun (3) , Manel Ben Halima (4) , Hedi Ben Slima (5) , Meriem Drissa (4) , Khadija Mzoughi (6) , Dorra Mbarek (7) , Leila Riahi (1) , Saoussen Antit (8) , Afef Ben Halima (3) , Wejdene Ouechtati (9) , Emna Allouche (9) , Mehdi Mechri (4) , Chedi Youssfi (2) , Ali Khorchani (10) , Kais Sammoud (4) , Khaled Zaouia (10) , Rami Tlili (7) , Sana Ouali (4) , Faten Triki (2) , Sonia Hamdi (11) , Selim Boudich (4) , Marwa Chebbi (4) , Mouna Hentati (12) , Amani Farah (13) , Habib Triki (14) , H. Ghardallou (15) , H. Radoui (16) , Sofien Zayed (13) , F. Azaiez (4) , Fadoua Omri (5) , Akram Zouari (2) , Zine Ben Ali (2) , A. Najjar (13) , Houssem Thabet (15) , Mouna Chaker (2) , Samar Mohammed (8) , Abdelhamid Ben Jmaa (2) , Haithem Tangour (15) , Yassine Kammoun (17) , Mahmoud Cheikh Bouhlel (15) , S. Azeiz (1) , R. Gtaief (1) , S. Mashki (1) , Aymen Amri (1) , Hela Naanea (1) , Raoudha Othmani (1) , Iheb Chahbani (1) , Houcine Zargouni (1) , Syrine Abid (1) , Mokded Ayari (1) , Ines Ben Ameur (1) , Ali Guesmi (18) , Nejeh Ben Halima (19) , Habib Haouala (11) , Wafa Fehri (11) , Essia Boughzela (15) , Lilia Zakhama (8) , Soraya Ben Youssef (8) , Wided Nasraoui (20) , Rachid Boujneh (7) , Nedia Barakett (21) , Sondos Kraiem (6) , Hbiba Drissa (4) , Ali Ben Khalfalah (22) , Habib Gamra (13) , Salem Kachboura (16) , Yosra Majdoub (2) , Elifa Kanoun (23) , Faiez Zannad (24, 25, 26, 27) , Sami Milouchi (10) , Alexandre Mebaza (28) , Samir Kammoun (2) , Sami Mourali (4) , Karima Hezbri (29) , Faouzi Addad (16)
Leila Abid
  • Function : Author
  • PersonId : 1101912
Salma Charfeddine
Ikram Kammoun
Manel Ben Halima
Hedi Ben Slima
Meriem Drissa
Khadija Mzoughi
Afef Ben Halima
Wejdene Ouechtati
Emna Allouche
Mehdi Mechri
Kais Sammoud
Sana Ouali
Marwa Chebbi
Amani Farah
Habib Triki
Sofien Zayed
Akram Zouari
Zine Ben Ali
Houssem Thabet
Mouna Chaker
Essia Boughzela
Habib Gamra
Salem Kachboura
Samir Kammoun

Abstract

The NATURE-HF registry was aimed to describe clinical epidemiology and 1-year outcomes of outpatients and inpatients with heart failure (HF). This is a prospective, multicenter, observational survey conducted in Tunisian Cardiology centers. A total of 2040 patients were included in the study. Of these, 1632 (80%) were outpatients with chronic HF (CHF). The mean hospital stay was 8.7 ± 8.2 days. The mortality rate during the initial hospitalization event for AHF was 7.4%. The all-cause 1-year mortality rate was 22.8% among AHF patients and 10.6% among CHF patients. Among CHF patients, the older age, diabetes, anemia, reduced EF, ischemic etiology, residual congestion and the absence of ACEI/ ARBs treatment were independent predictors of 1-year cumulative rates of rehospitalization and mortality. The female sex and the functional status were independent predictors of 1-year all-cause mortality and rehospitalization in AHF patients. This study confirmed that acute HF is still associated with a poor prognosis, while the mid-term outcomes in patients with chronic HF seems to be improved. Some differences across countries may be due to different clinical characteristics and differences in healthcare systems.
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Dates and versions

hal-03258487 , version 1 (11-06-2021)

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Leila Abid, Salma Charfeddine, Ikram Kammoun, Manel Ben Halima, Hedi Ben Slima, et al.. Epidemiology of heart failure and long-term follow-up outcomes in a north-African population: Results from the NAtional TUnisian REgistry of Heart Failure (NATURE-HF). PLoS ONE, 2021, 16 (5), pp.e0251658. ⟨10.1371/journal.pone.0251658⟩. ⟨hal-03258487⟩
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