Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension - Université de Lorraine Access content directly
Journal Articles Science Translational Medicine Year : 2017

Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension

Sabine Kossmann
Jeremy Lagrange
Sven Jäckel
  • Function : Author
Kerstin Jurk
  • Function : Author
Moritz Ehlken
  • Function : Author
Tanja Schönfelder
  • Function : Author
Yvonne Weihert
  • Function : Author
Maike Knorr
  • Function : Author
Moritz Brandt
  • Function : Author
Ning Xia
Huige Li
Andreas Daiber
Matthias Oelze
  • Function : Author
Christoph Reinhardt
  • Function : Author
Karl Lackner
  • Function : Author
Andras Gruber
  • Function : Author
Brett Monia
  • Function : Author
Susanne Karbach
Ulrich Walter
  • Function : Author
Zaverio Ruggeri
  • Function : Author
Thomas Renné
  • Function : Author
Wolfram Ruf
Thomas Münzel
Philip Wenzel

Abstract

Blockade of an inflammatory, thrombin-activated feedback loop on platelets controls high blood pressure.
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Dates and versions

hal-03641717 , version 1 (14-04-2022)

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Cite

Sabine Kossmann, Jeremy Lagrange, Sven Jäckel, Kerstin Jurk, Moritz Ehlken, et al.. Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension. Science Translational Medicine, 2017, 9 (375), ⟨10.1126/scitranslmed.aah4923⟩. ⟨hal-03641717⟩

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