Correlation of Quantitated Intravascular Volume with Blood Pressure in Patients with Systemic Hypertension - Université de Lorraine Access content directly
Journal Articles Journal of Cardiovascular Translational Research Year : 2020

Correlation of Quantitated Intravascular Volume with Blood Pressure in Patients with Systemic Hypertension

Abstract

Introduction: Volume management is an essential component of anti-hypertensive therapy. Different volume phenotypes have been proposed. We sought to study the total blood volume (TBV), plasma volume (PV) and red blood cell volume (RBV) in hypertensive patients. Methods: We included patients followed in an outpatient cardiology clinic from 1998-2003. Blood volume (BV) parameters were measured using radioisotope iodine-131-labeled albumin dilution technique. Values were expressed as percentage (%) deviation from ideal volumes. Results: A total of 95 patients were included. The intravascular volume distribution as percent deviation from normal volume ranged from-23% to +28% for TBV,-22% to +36% for PV and-29% to +37% for RBV. There was no significant correlation between systolic BP and any of the BV parameters (TBV and SBP, r=-0.03; PV and SBP, r=-0.12; RBV and SBP, r=-0.08). Discussion: Patients with hypertension have a wide variation in BV parameters. BV does not correlate with SBP.
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hal-03754627 , version 1 (19-08-2022)

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Marat Fudim, Vanessa L Blumer, Renato D Lopes, Patrick Rossignol, Michael Feldschuh, et al.. Correlation of Quantitated Intravascular Volume with Blood Pressure in Patients with Systemic Hypertension. Journal of Cardiovascular Translational Research, 2020, 13 (4), pp.528-530. ⟨10.1007/s12265-019-09910-4⟩. ⟨hal-03754627⟩
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