CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease
Christopher Ma
(1)
,
Jurij Hanzel
(2, 3)
,
Remo Panaccione
(1)
,
William Sandborn
(4)
,
Geert d'Haens
(5)
,
Vineet Ahuja
(6)
,
Raja Atreya
(7, 8)
,
Charles Bernstein
(9)
,
Peter Bossuyt
(10)
,
Brian Bressler
(11)
,
Robert Bryant
(12)
,
Benjamin Cohen
(13)
,
Jean-Frederic Colombel
(14)
,
Silvio Danese
(15, 16)
,
Axel Dignass
(17)
,
Marla Dubinsky
(14)
,
Phillip Fleshner
(18)
,
Richard Gearry
(19)
,
Stephen Hanauer
(20)
,
Ailsa Hart
(21)
,
Paulo Gustavo Kotze
(22)
,
Torsten Kucharzik
(23)
,
Peter Lakatos
(24, 25)
,
Rupert Leong
(26)
,
Fernando Magro
(27)
,
Julian Panés
(28)
,
Laurent Peyrin‐biroulet
(29, 30)
,
Zhihua Ran
(31)
,
Miguel Regueiro
(13)
,
Siddharth Singh
(4)
,
Antonino Spinelli
(32, 33)
,
A Hillary Steinhart
(34, 35)
,
Simon Travis
(36)
,
C Janneke van der Woude
(37)
,
Bruce Yacyshyn
(38)
,
Takayuki Yamamoto
,
Matthieu Allez
(39, 40)
,
Willem Bemelman
(5)
,
Amy Lightner
(13)
,
Edouard Louis
(41)
,
David Rubin
(42)
,
Ellen Scherl
(43)
,
Corey Siegel
(44)
,
Mark Silverberg
(34)
,
Severine Vermeire
(45, 46)
,
Claire Parker
,
Stefanie Mcfarlane
,
Leonardo Guizzetti
,
Michelle Smith
,
Niels Vande Casteele
(4)
,
Brian Feagan
(47)
,
Vipul Jairath
(47)
,
Geert D’haens
,
A. Hillary Steinhart
,
C. Janneke van der Woude
1
University of Calgary
2 University of Ljubljana
3 UMCL - University Medical Centre Ljubljana [Ljubljana, Slovenia]
4 UC San Diego - University of California [San Diego]
5 Amsterdam UMC - Amsterdam University Medical Centers
6 All India Institute of Medical Sciences [New Delhi]
7 University Hospital Erlangen = Uniklinikum Erlangen
8 FAU - Friedrich-Alexander Universität Erlangen-Nürnberg = University of Erlangen-Nuremberg
9 University of Manitoba [Winnipeg]
10 Imelda General Hospital
11 SPH-UBC - St. Paul’s Hospital - University of British Columbia [Vancouver, BC, Canada]
12 University of Adelaide
13 Cleveland Clinic
14 MSSM - Icahn School of Medicine at Mount Sinai [New York]
15 UniSR - Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie]
16 IRCCS Ospedale San Raffaele [Milan, Italy]
17 Goethe-Universität Frankfurt am Main
18 Cedars-Sinai Medical Center
19 University of Otago [Dunedin, Nouvelle-Zélande]
20 Northwestern University [Chicago, Ill. USA]
21 NPH - Northwick Park Hospital [Harrow, UK]
22 PUCPR - Pontifícia Universidade Católica do Paraná [Curitiba, Brasil] = Pontifical Catholic University of Paraná [Curitiba, Brazil] = Université catholique pontificale du Paraná [Curitiba, Brésil]
23 UHH - Universität Hamburg
24 McGill University = Université McGill [Montréal, Canada]
25 Semmelweis University [Budapest]
26 The University of Sydney
27 Universidade do Porto = University of Porto
28 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
29 NGERE - Nutrition-Génétique et Exposition aux Risques Environnementaux
30 Service d'Hépato-gastro-entérologie [CHRU Nancy]
31 Shanghai Jiao Tong University [Shanghai]
32 Hunimed - Humanitas University [Milan]
33 IRCCS S. Maria Nascente - Istituto di Ricovero e Cura a Carattere Scientifico
34 MSH - Mount Sinai Hospital [Toronto, Canada]
35 University of Toronto
36 John Radcliffe Hospital [Oxford University Hospital]
37 Erasmus MC - Erasmus University Medical Center [Rotterdam]
38 UC - University of Cincinnati
39 EMily (UMR_S_1160 / U1160) - Ecotaxie, microenvironnement et développement lymphocytaire
40 AP-HP - Hopital Saint-Louis [AP-HP]
41 CHU-Liège - Centre Hospitalier Universitaire de Liège
42 The University of Chicago Medicine [Chicago]
43 Weill Cornell Medicine [Cornell University]
44 DHMC - Dartmouth Hitchcock Medical Center
45 University Hospitals Leuven [Leuven]
46 KU Leuven - Catholic University of Leuven = Katholieke Universiteit Leuven
47 UWO - University of Western Ontario
2 University of Ljubljana
3 UMCL - University Medical Centre Ljubljana [Ljubljana, Slovenia]
4 UC San Diego - University of California [San Diego]
5 Amsterdam UMC - Amsterdam University Medical Centers
6 All India Institute of Medical Sciences [New Delhi]
7 University Hospital Erlangen = Uniklinikum Erlangen
8 FAU - Friedrich-Alexander Universität Erlangen-Nürnberg = University of Erlangen-Nuremberg
9 University of Manitoba [Winnipeg]
10 Imelda General Hospital
11 SPH-UBC - St. Paul’s Hospital - University of British Columbia [Vancouver, BC, Canada]
12 University of Adelaide
13 Cleveland Clinic
14 MSSM - Icahn School of Medicine at Mount Sinai [New York]
15 UniSR - Universita Vita Salute San Raffaele = Vita-Salute San Raffaele University [Milan, Italie]
16 IRCCS Ospedale San Raffaele [Milan, Italy]
17 Goethe-Universität Frankfurt am Main
18 Cedars-Sinai Medical Center
19 University of Otago [Dunedin, Nouvelle-Zélande]
20 Northwestern University [Chicago, Ill. USA]
21 NPH - Northwick Park Hospital [Harrow, UK]
22 PUCPR - Pontifícia Universidade Católica do Paraná [Curitiba, Brasil] = Pontifical Catholic University of Paraná [Curitiba, Brazil] = Université catholique pontificale du Paraná [Curitiba, Brésil]
23 UHH - Universität Hamburg
24 McGill University = Université McGill [Montréal, Canada]
25 Semmelweis University [Budapest]
26 The University of Sydney
27 Universidade do Porto = University of Porto
28 IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer
29 NGERE - Nutrition-Génétique et Exposition aux Risques Environnementaux
30 Service d'Hépato-gastro-entérologie [CHRU Nancy]
31 Shanghai Jiao Tong University [Shanghai]
32 Hunimed - Humanitas University [Milan]
33 IRCCS S. Maria Nascente - Istituto di Ricovero e Cura a Carattere Scientifico
34 MSH - Mount Sinai Hospital [Toronto, Canada]
35 University of Toronto
36 John Radcliffe Hospital [Oxford University Hospital]
37 Erasmus MC - Erasmus University Medical Center [Rotterdam]
38 UC - University of Cincinnati
39 EMily (UMR_S_1160 / U1160) - Ecotaxie, microenvironnement et développement lymphocytaire
40 AP-HP - Hopital Saint-Louis [AP-HP]
41 CHU-Liège - Centre Hospitalier Universitaire de Liège
42 The University of Chicago Medicine [Chicago]
43 Weill Cornell Medicine [Cornell University]
44 DHMC - Dartmouth Hitchcock Medical Center
45 University Hospitals Leuven [Leuven]
46 KU Leuven - Catholic University of Leuven = Katholieke Universiteit Leuven
47 UWO - University of Western Ontario
Christopher Ma
- Fonction : Auteur
- PersonId : 1271362
- ORCID : 0000-0002-4698-9948
Laurent Peyrin‐biroulet
- Fonction : Auteur
- PersonId : 1111110
- ORCID : 0000-0003-2536-6618
- IdRef : 087640147
Takayuki Yamamoto
- Fonction : Auteur
Claire Parker
- Fonction : Auteur
Stefanie Mcfarlane
- Fonction : Auteur
Leonardo Guizzetti
- Fonction : Auteur
Michelle Smith
- Fonction : Auteur
Geert D’haens
- Fonction : Auteur
A. Hillary Steinhart
- Fonction : Auteur
C. Janneke van der Woude
- Fonction : Auteur
Résumé
End points to determine the efficacy and safety of medical therapies for Crohn's disease (CD) and ulcerative colitis (UC) are evolving. Given the heterogeneity in current outcome measures, harmonizing end points in a core outcome set for randomized controlled trials is a priority for drug development in inflammatory bowel disease.