Green-Mediated Synthesis of NiCo2O4 Nanostructures Using Radish White Peel Extract for the Sensitive and Selective Enzyme-Free Detection of Uric Acid - Université de Lorraine Accéder directement au contenu
Article Dans Une Revue Biosensors Année : 2023

Green-Mediated Synthesis of NiCo2O4 Nanostructures Using Radish White Peel Extract for the Sensitive and Selective Enzyme-Free Detection of Uric Acid

Abdul Ghaffar Solangi
  • Fonction : Auteur
Aneela Tahira
  • Fonction : Auteur
  • PersonId : 1281269
Baradi Waryani
  • Fonction : Auteur
  • PersonId : 1281270
Tajnees Pirzada
  • Fonction : Auteur
  • PersonId : 1281271
Ayman Nafady
  • Fonction : Auteur
  • PersonId : 1038710
Elmuez A Dawi
  • Fonction : Auteur
  • PersonId : 1281272
Mohsen Padervand
  • Fonction : Auteur
  • PersonId : 1281274
Abd Al Karim Haj Ismail
  • Fonction : Auteur
  • PersonId : 1281275
Kangle Lv
  • Fonction : Auteur
  • PersonId : 1281276
Brigitte Vigolo
  • Fonction : Auteur
  • PersonId : 1281277
Zafar Hussain Ibupoto

Résumé

The ability to measure uric acid (UA) non-enzymatically in human blood has been demonstrated through the use of a simple and efficient electrochemical method. A phytochemical extract from radish white peel extract improved the electrocatalytic performance of nickel–cobalt bimetallic oxide (NiCo2O4) during a hydrothermal process through abundant surface holes of oxides, an alteration of morphology, an excellent crystal quality, and increased Co(III) and Ni(II) chemical states. The surface structure, morphology, crystalline quality, and chemical composition were determined using a variety of analytical techniques, including powder X-ray diffraction (XRD), scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HR-TEM), and X-ray photoelectron spectroscopy (XPS). The electrochemical characterization by CV revealed a linear range of UA from 0.1 mM to 8 mM, with a detection limit of 0.005 mM and a limit of quantification (LOQ) of 0.008 mM. A study of the sensitivity of NiCo2O4 nanostructures modified on the surface to UA detection with amperometry has revealed a linear range from 0.1 mM to 4 mM for detection. High stability, repeatability, and selectivity were associated with the enhanced electrochemical performance of non-enzymatic UA sensing. A significant contribution to the full outperforming sensing characterization can be attributed to the tailoring of surface properties of NiCo2O4 nanostructures. EIS analysis revealed a low charge-transfer resistance of 114,970 Ohms that offered NiCo2O4 nanostructures prepared with 5 mL of radish white peel extract, confirming an enhanced performance of the presented non-enzymatic UA sensor. As well as testing the practicality of the UA sensor, blood samples from human beings were also tested for UA. Due to its high sensitivity, stability, selectivity, repeatability, and simplicity, the developed non-enzymatic UA sensor is ideal for monitoring UA for a wide range of concentrations in biological matrixes.

Domaines

Chimie
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Dates et versions

hal-04198622 , version 1 (07-09-2023)

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Citer

Abdul Ghaffar Solangi, Aneela Tahira, Baradi Waryani, Abdul Sattar Chang, Tajnees Pirzada, et al.. Green-Mediated Synthesis of NiCo2O4 Nanostructures Using Radish White Peel Extract for the Sensitive and Selective Enzyme-Free Detection of Uric Acid. Biosensors, 2023, 13 (8), pp.780. ⟨10.3390/bios13080780⟩. ⟨hal-04198622⟩
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