How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC - Université de Lorraine Access content directly
Journal Articles European Journal of Heart Failure Year : 2024

How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC

1 Karolinska Institutet [Stockholm]
2 Karolinska University Hospital [Stockholm]
3 King‘s College London
4 KCH - King's College Hospital
5 Emergency Institute for Cardiovascular Diseases “Prof. Dr. C.C. Iliescu” [Bucharest, Romania]
6 UMPCD - University of Medicine and Pharmacy “Carol Davila” Bucharest
7 Università degli studi di Trieste = University of Trieste
8 Santa Maria delle Grazie Hospital
9 UniBs - Università degli Studi di Brescia = University of Brescia
10 Cairo University - Faculty of Medicine
11 St George's, University of London
12 St George’s University Hospitals
13 Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV)
14 GTPUH - Germans Trias i Pujol University Hospital [Badalona, Barcelona, Spain]
15 Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
16 Heart Research Institute
17 CIC-P - Centre d'investigation clinique plurithématique Pierre Drouin [Nancy]
18 INI-CRCT - Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy]
19 Cardiovascular & Renal Clinical Trialists - CRCT - French-Clinical Research Infrastructure Network - F-CRIN [Paris]
20 DCAC - Défaillance Cardiovasculaire Aiguë et Chronique
21 Wrocław Medical University
22 QUB - Queen's University [Belfast]
23 University of Ljubljana
24 VSMU - Volgograd State Medical University [Russian Federation]
25 ANMCO - Associazione Nazionale Medici Cardiologi Ospedalieri [Firenze]
26 FMUP - Faculdade de Medicina da Universidade do Porto
27 Hospital das Forcas Armadas [Porto, Portugal]
28 Konaev City Hospital
29 SASA - Serbian Academy of Sciences and Arts
30 University of Belgrade [Belgrade]
31 UOB - University of Balamand [Liban]
32 San Raffaele Open University of Rome
33 San Raffaele Hospital
Ewa A. Jankowska
  • Function : Author
  • PersonId : 1214068
Hadi Skouri

Abstract

Abstract Guideline‐directed medical therapy (GDMT) in patients with heart failure and reduced ejection fraction (HFrEF) reduces morbidity and mortality, but its implementation is often poor in daily clinical practice. Barriers to implementation include clinical and organizational factors that might contribute to clinical inertia, i.e. avoidance/delay of recommended treatment initiation/optimization. The spectrum of strategies that might be applied to foster GDMT implementation is wide, and involves the organizational set‐up of heart failure care pathways, tailored drug initiation/optimization strategies increasing the chance of successful implementation, digital tools/telehealth interventions, educational activities and strategies targeting patient/physician awareness, and use of quality registries. This scientific statement by the Heart Failure Association of the ESC provides an overview of the current state of GDMT implementation in HFrEF, clinical and organizational barriers to implementation, and aims at suggesting a comprehensive framework on how to overcome clinical inertia and ultimately improve implementation of GDMT in HFrEF based on up‐to‐date evidence.
Fichier principal
Vignette du fichier
European J of Heart Fail - 2024 - Savarese - How to tackle therapeutic inertia in heart failure with reduced ejection.pdf (1.41 Mo) Télécharger le fichier
Origin Publisher files allowed on an open archive
Licence

Dates and versions

hal-04586157 , version 1 (24-05-2024)

Licence

Identifiers

Cite

Gianluigi Savarese, Felix Lindberg, Antonio Cannata, Ovidiu Chioncel, Davide Stolfo, et al.. How to tackle therapeutic inertia in heart failure with reduced ejection fraction. A scientific statement of the Heart Failure Association of the ESC. European Journal of Heart Failure, 2024, ⟨10.1002/ejhf.3295⟩. ⟨hal-04586157⟩
0 View
0 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More