Évaluation de l'exposition professionnelle à l'éthanol contenu dans les solutions hydroalcooliques utilisées dans la lutte contre les infections nosocomiales

Abstract : Previous studies have shown that the use of Acohol-Based Hand Rubs (ABHRs) has been associated with reduced rates of nosocomial infections. However, the quality of hand rubbing with ABHRs has rarely been evaluated. The first aim of this work is to evaluate the quality of hand rubbing and skin tolerance to ABHRs in the long term. The consequences of systemic passage of alcohol by inhalation or dermal absorption during intensive use of these products in hospitals remain a subject of debate. The second aim of our work is to assess the exposure of Healthcare Workers (HCWs) to ABHRs, under experimental conditions in the laboratory and under a real situation of work shift in hospital. Our study demonstrated a decrease in the quality of hand rubbing. The use of these products increases skin hydration. ABHRs are well tolerated by HCWs and do not dry the skin.The measurements made in the laboratory showed that exposure to ethanol during ABHRs handling is of short duration but at high concentrations. The quantification of ethanol in ambient air of a patient room for eight hours of ABHRS intensive use showed that the patient and HCW are exposed to the same amount of ethanol vapours. However this amount remains far inferior to the French guidelines for professional exposure limits to ethanol over 8 hours. The hospital study showed that exposure of HCWs to ABHR at short term does not lead to detectable absorption of ethanol and its metabolites. Quantification of ethanol vapour in the inhaled air remains well below the levels known to be toxic in humans. The whole project takes place over 10 years; it will verify the potential side effects associated with the ABHRs use for a long-term
Document type :
Theses
Complete list of metadatas

https://hal.univ-lorraine.fr/tel-01749663
Contributor : Thèses Ul <>
Submitted on : Thursday, March 29, 2018 - 12:22:41 PM
Last modification on : Monday, April 23, 2018 - 3:53:23 PM
Long-term archiving on: Friday, September 14, 2018 - 8:31:49 AM

File

DDOC_T_2012_0337_AHMED_LECHEHE...
Files produced by the author(s)

Identifiers

  • HAL Id : tel-01749663, version 1

Collections

Citation

Djihane Ahmed Lecheheb. Évaluation de l'exposition professionnelle à l'éthanol contenu dans les solutions hydroalcooliques utilisées dans la lutte contre les infections nosocomiales. Médecine humaine et pathologie. Université de Lorraine, 2012. Français. ⟨NNT : 2012LORR0337⟩. ⟨tel-01749663⟩

Share

Metrics

Record views

38

Files downloads

18