Mise en oeuvre d'un modèle mécanique de l'adhésion cellulaire : approche stochastique

Abstract : Cell adhesion is an important phenomenon in biology, especially in the immune defence and tissue growth.We focus in this work on the development of a mechanical model for the description of the cell adhesion in a multiscal context. The first one is microscopic scale, which describes the molecular rupture and adhesion kinetics.At the mesoscopic scale, we model the active deformation of the cell during the motility phenomenon. At the macroscopic scale, we model the time evolution of the adhesion of cell population, under the action of the fluid. Numerical simulations emphasize the rolling phenomenon and the active deformation of a cell
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Ali Mefti. Mise en oeuvre d'un modèle mécanique de l'adhésion cellulaire : approche stochastique. Autre [cond-mat.other]. Institut National Polytechnique de Lorraine, 2006. Français. ⟨NNT : 2006INPL099N⟩. ⟨tel-01752788⟩

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